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View Sepax featured Filters, Couplers, Kits and FPLC Accessories which will boot your lab efficiency
Sepax Technologies
USA based leading chromatography product manufacturer and service provider specializing in biological separation areas.
List of Products from this Brand
Antibodix WCX
The packing support is composed of a rigid, spherical, highly cross-linked poly(styrene divinylbenzene) (PS/DVB) non-porous bead. The non-porous resin has particle size of 1.7, 3, 5 and 10 µm. The PS/DVB resin surface is grafted with a highly hydrophilic, neutral polymer thin layer with the thickness in the range of nanometer. On the top of the hydrophilic layer, weak cation-exchange functional groups are attached via a proprietary chemistry, resulting in high capacity ion-exchange layer.
Bio-C18
The specially designed surface bonding chemistry and the pore sizes allow for extended retention and selectivity for polar and hydrophilic compounds, such as peptides and amino acids. C18 monolayer formed by special bonding chemistry does not collapse in pure aqueous solution.
Bio-C4
Monomeric and fully endcapped Bio-C4 packing is bonded with butyl groups that lead to moderate hydrophobicity. Bio-C4 packings of 300 Å pore size selection are ideal for high resolution mapping of peptides and separation of intact proteins, and natural and synthetic peptides.
Bio-C8
The uniform stationary phase allows the separation to achieve high selectivity and high efficiency. Bio-C8 packings of 300 Å pore size selection are ideal for high resolution mapping of peptides and separation of natural and synthetic peptides and small proteins.
BIOMIX SEC
The proprietary surface technologies allow the chemistry of thin film formation to be well controlled, which results in high column-to-column reproducibility. The nature of the chemical bonding and the uniformity of the thin film benefit BioMix-300 phase with high stability. BioMix-300 resin is produced from 3 µm spherical silica particles with a pore size of 300 Å. BioMix-300 columns are packed with a proprietary slurry technique to achieve uniform and stable packing bed density for maximum column efficiency. BioMix-300 phase is designed to ensure highest resolution and maximum recovery for a broad range of analytes such as bispecific mAb, hydrophobic samples etc.
BioService Affinity HSA
Albumin also transports many endogenous molecules, including hormones, fatty acids, metabolites, and other exogenous compounds, including drugs. It also buffers pH and maintains oncotic pressure.1 Therefore, HSA can greatly influence drug half-life, which is critical to pharmacokinetics and efficacy. Because of HSA’s critical role in drug transport, it is imperative and necessary to assess potential drug interactions during the development of modern therapeutics, such as Monoclonal Antibodies (mAbs). A well-controlled method to assess such immune cross-reactivity in vitro would be to immobilize HSA to a specific biocompatible resin matrix and evaluate the degree of interaction of HSA with a target mAb of interest.
BR-C18
Utilizing highest purity and enhanced mechanical stability silica and pure bonding reagents, BR-C18 bonded phases have been innovatively and specially designed to ensure maximum surface coverage and full end-capping, which leads to carbon content as high as 19.0%. The bonding chemistry is completely controlled that results in very reliable column-to-column reproducibility. The maximum surface coverage allows BR-C18 to have exceptional stability, resulting in high pH stability in the range of 1.5 to 10.5.
Carbomix
Carbomix phases are composed of spherical, low cross-linking polystyrene/divinylbenzene (PS/DVB) particles with their surfaces modified with sulfonic acid (-SO3H), followed by chelating of metal ions of calcium (Ca2+), lead (Pb2+), sodium (Na+) or potassium (K+) to form Carbomix Ca-NP, Pb-NP, Na-NP, K-NP phases, respectively. The PS/DVB support has cross-linking degree of 5%, 8% and 10% with the particle sizes of 5 and 10 µm. The uniform particle size adds the benefit of high separation efficiency to Carbomix. Carbomix resins have been specifically designed for high resolution separation of carbohydrates, organic acids, peptides, and nucleic acids.
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