Chromatography

Column packing material comprises of a fully endcapped trifunctional C18 ligand bonded to a Charged Surface Hybrid (CSH) substrate, enabling more reproducible chromatographic performance with better peak shape and recovery for metal-sensitive analytes. Column works particularly well with 0.1% formic acid for LC or LC-MS applications, and is specifically QC tested with a tryptic digest of cytochrome c using 0.1% formic acid containing eluents due to its low and carefully-defined concentration of positive charges.

Column packing material comprises of an endcapped intermediate bonded C18 ligand bonded to a High Strength Silica (HSS) substrate, enabling exceptional retention and peak shape for all compounds. Its compatibility with aqueous mobile phase enables separations of polar and non-polar compounds. Column is packed in ultra-low dispersion hardware, enabling exceptional separation performance, robustness and throughput for HPLC assays while enabling transition towards adopting UPLC.

Explore advanced HPLC post-column derivatization with Pinnacle PCX by Pickering Laboratories. Tailored for amino acids, carbamates, mycotoxins, antibiotics, and more. Ensure unmatched sensitivity and selectivity with our integrated system.

The imidazole ring is polar and nitrogen-containing, and can act as a weak base under certain mobile phase conditions. This stationary phase is suitable for separations of pharmaceuticals, peptides, sugars, and nucleotides.

These highly rigid particles have both non-porous and porous structures with the particle size selection of 1.7, 3, 5, and 10 µm. The phase structure is phenyl functional groups that enable hydrophobic interaction. Compared with silica based reversed phases, PolyRP phases have advantages over applications at extreme pH (1-14) with special selectivity and slightly lower separation efficiency.

SIELC Technologies presents Primesep® HPLC columns, challenging traditional norms by leveraging mixed-mode interactions. Specifically designed for diverse separations, these columns excel in compound versatility, offering tailored solutions without compromise.

The base resin is composed of monosized 20 µm, 1000–2000 Å highly cross-linked PS/DVB beads coupled with a recombinant Protein A ligand, which selectively binds Fc-containing immunoglobulins except IgG3. The resin exhibits excellent mechanical robustness and can tolerate high-flow and high-pressure operation, making it well suited for high-throughput analytical workflows.

Promix MP, designed for 1-10 kDa proteins and peptides, features a broad pI range, utilizing reverse phase and ion-exclusion interactions. Accommodate diverse applications with acidic mobile phase (pH 2-5.5) and varied pore sizes.

Column packing material comprises of a proprietary monofunctional bonded C4 ligand bonded to an Ethylene Bridge Hybrid (BEH) substrate. Column is optimised to separate proteins based on size, hydrophobicity and isoelectric point, and is specially QC tested with protein mixture.