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Proteomix POR50-dT20
Sepax Proteomix POR50-dT20 Affinity Resin is a monodispersed PS/DVB base bead that has a profuse porous structure with large through pores, good physical and chemical stability and good pressure resistance.
Sepax Technologies
Description
Oligo dT20-mer is conjugated to the bead surface through a proprietary method. The resulting affinity resin is specially designed and highly optimized for the isolation of messenger RNA (mRNA). Most mRNA molecules contain a tail of poly(adenylic acid) (polyA tail), up to 250 bases in length. The Proteomix POR dT20 Affinity Resin surface allows capture of mRNA through base pairing between oligo dT20-mer and the mRNA polyA tail using a simple and convenient chromatography procedure.
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Features
Specifications
- Provides efficient capture and release under standard mRNA purification conditions, simplifies subsequent purification steps, and maximizes overall production efficiency
- Large pore sizes which enables high loading capacity for large mRNAs, easier elution, and high recovery rate
- Decreases process development time and enhances productivity
- Allows reduction in plasmid DNA and other transcription mix components
- Stable at elevated temperatures for the breakdown of undesired higher order structures, if needed
- Excellent scalability. Available as prepacked columns, semi-prep columns, prep columns, and bulk resin
- Non-animal derived
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